Overview

What is Neurobolix™?

Neurobolix™ is a precision-formulated pre-training cognitive performance strip combining two of the most studied compounds in modern performance neuroscience — Tesofensine and 5-Amino-1MQ — in a single fast-dissolving thin film.

Where most pre-workouts chase a stimulant rush through caffeine and synthetic compounds, Neurobolix™ works differently. It targets the neurochemical and metabolic systems that govern genuine cognitive performance — focus, drive, mind-muscle connection, and sustained mental stamina under physical load.

The result is a clean, locked-in mental state built for training — without the jitteriness, anxiety, or crash that follow most stimulant-based pre-workouts.

• Tesofensine — 500 mcg — triple monoamine reuptake inhibitor for focus, drive, and mental performance
• 5-Amino-1MQ — 500 mcg — NNMT inhibitor for cellular energy, metabolic efficiency, and NAD+ support

Mechanism

The science behind the formula

Tesofensine — 500 mcg

Tesofensine was originally developed as a neurological drug — first investigated for Parkinson’s disease and later for obesity management. What researchers discovered was a compound that produced powerful and consistent improvements in focus, motivation, cognitive clarity, and drive.

Tesofensine is a triple monoamine reuptake inhibitor — it simultaneously inhibits the reuptake of three key neurotransmitters:

• Dopamine — the neurotransmitter of motivation, drive, reward, and goal-directed behavior. Supports the focused, motivated mental state needed for productive training.
• Norepinephrine — the neurotransmitter of alertness, arousal, and physical readiness. Sharpens attention, heightens sensory awareness, and supports mind-body connection during physical performance.
• Serotonin — the neurotransmitter of mood stability and emotional regulation. Maintains a positive, stable mental state rather than the anxious edge associated with pure dopamine/norepinephrine stimulants.

What this means for training: sharper pre-lift mental lock-in, stronger drive and motivation, heightened mind-muscle connection, sustained focus through the full session, and a positive stable mood throughout.

5-Amino-1MQ — 500 mcg

5-Amino-1MQ is a selective inhibitor of Nicotinamide N-Methyltransferase (NNMT) — an enzyme that plays a key role in cellular metabolism and energy regulation. It works at the metabolic and cellular energy layer that powers everything your brain and body do during training.

• Supports NAD+ production — By inhibiting NNMT, 5-Amino-1MQ preserves NAD+ precursor availability — supporting higher cellular NAD+ levels, mitochondrial energy production, DNA repair, and cellular metabolism.
• Enhances mitochondrial efficiency — Helps the brain and body produce energy more efficiently — reducing the metabolic fatigue that degrades mental performance under physical load.
• Supports metabolic optimization — Studied for its role in metabolic efficiency and body composition — supporting the cellular environment that favors lean tissue and efficient energy utilization.

Why the combination works

Tesofensine works at the neurotransmitter level — optimizing the signaling chemicals that drive focus, motivation, and mind-muscle connection. 5-Amino-1MQ works at the metabolic level — optimizing the cellular energy systems that sustain performance under load. Together they address both the neurochemical and bioenergetic foundations of cognitive performance.

Applications

Who is Neurobolix™ for?

• Strength & power athletes — For lifters who need to be fully mentally locked in. Supports the focused, driven mental state where every rep is intentional and every set is executed with purpose.
• Endurance & performance athletes — Mental stamina under sustained physical load is just as important as physical conditioning. Supports the cognitive staying power to maintain focus, form, and drive through long training sessions.
• High-performance professionals — For anyone who needs to perform cognitively under pressure — the focused, motivated, clear mental state Neurobolix™ produces applies equally to high-demand professional and competitive environments.
• Bodybuilders & physique competitors — For those who need to bring maximum intensity and mind-muscle connection to every training session — particularly during prep phases where fatigue and caloric deficit can erode mental sharpness.

Format

Why a dissolving strip?

The thin-film dissolving strip format was chosen for Neurobolix™ for specific performance reasons:

• Fast onset — dissolves on the tongue in seconds for rapid absorption
• Pre-training convenience — no mixing, no shakers, no prep — take it anywhere
• Precise dosing — each strip contains exactly 500 mcg of each active ingredient
• Travel-friendly — fits in any gym bag, pocket, or kit
• No filler ingredients — no artificial colors, no excessive inactive ingredients
• Pharmaceutical-grade quality — manufactured to the highest standards

Evidence

What does the research say?

• Tesofensine — Originally investigated in clinical trials for Parkinson’s disease and obesity management, Tesofensine consistently demonstrated significant improvements in cognitive function, focus, and motivation as secondary outcomes. Its triple reuptake mechanism produces more comprehensive and balanced cognitive enhancement than single-target stimulants — with documented effects on alertness, attention, and executive function.
• 5-Amino-1MQ — Preclinical research has demonstrated its ability to inhibit NNMT activity, support NAD+ precursor availability, and improve markers of metabolic efficiency. Studies have shown its role in supporting mitochondrial function and cellular energy production — the metabolic foundation of sustained physical and cognitive performance.

Note: While both compounds have been studied in research settings, they are not FDA-approved for cognitive enhancement or sports performance purposes. Neurobolix™ is sold as a wellness supplement and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use.

Safety

Is it safe?

Tesofensine is a potent CNS-active compound — start with caution and assess your individual response carefully.

• Not suitable for individuals with cardiovascular disease or hypertension — Tesofensine can elevate heart rate and blood pressure
• Not suitable for individuals with anxiety disorders — triple monoamine reuptake inhibition may exacerbate anxiety in sensitive individuals
• Do not combine with other stimulants, MAOIs, SSRIs, or SNRIs
• Not suitable for pregnant or breastfeeding individuals
• Not suitable for those under 18 years of age
• Neither compound is FDA-approved for human performance use
• Always consult your healthcare provider before starting Neurobolix™

Product Details

Specifications

FAQ

Frequently asked questions